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1

Enhancing the intestinal absorption of poorly water-soluble weak-acidic compound by controlling local pH

Iwanaga, Kazunori, Kato, Shino, Miyazaki, Makoto, Kakemi, Masawo

Journal:

Drug Development and Industrial Pharmacy

Year:

2013

Language:

english

File:

PDF, 773 KB

english, 2013

2

Application of organogels as oral controlled release formulations of hydrophilic drugs

Kazunori Iwanaga, Mineo Kawai, Makoto Miyazaki, Masawo Kakemi

Journal:

International Journal of Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 404 KB

english, 2012

3

Effect of chlorpromazine on the pharmacokinetics and pharmacodynamics of pentobarbital in rats.

HATANAKA, Tomomi, SATO, Shinji, ENDOH, Makiko, KATAYAMA, Kazunori, KAKEMI, Masawo, KOIZUMI, Tamotsu

Journal:

Journal of Pharmacobio-Dynamics

Year:

1988

File:

PDF, 1.21 MB

1988

4

Characterization of organogel as a novel oral controlled release formulation for lipophilic compounds

Kazunori Iwanaga, Toru Sumizawa, Makoto Miyazaki, Masawo Kakemi

Journal:

International Journal of Pharmaceutics

Year:

2010

Language:

english

File:

PDF, 437 KB

english, 2010

5

Oral delivery of insulin by using surface coating liposomes: Improvement of stability of insulin in GI tract

Kazunori Iwanaga, Satoshi Ono, Kohji Narioka, Kazuhiro Morimoto, Masawo Kakemi, Shinji Yamashita, Mamoru Nango, Naoto Oku

Journal:

International Journal of Pharmaceutics

Year:

1997

Language:

english

File:

PDF, 112 KB

english, 1997

6

Effects of sodium glycocholate and protease inhibitors on permeability of TRH and insulin across rabbit trachea

Kazuhiro Morimoto, Yuriko Uehara, Kazunori Iwanaga, Masawo Kakemi

Journal:

Pharmaceutica Acta Helvetiae

Year:

2000

Language:

english

File:

PDF, 116 KB

english, 2000

7

Disposition of Lipid-Based Formulation in the Intestinal Tract Affects the Absorption of Poorly Water-Soluble Drugs

Iwanaga, Kazunori, Kushibiki, Toshihiro, Miyazaki, Makoto, Kakemi, Masawo

Journal:

Biological & Pharmaceutical Bulletin

Year:

2006

Language:

english

File:

PDF, 116 KB

english, 2006

8

Application of surface-coated liposomes for oral delivery of peptide: Effects of coating the liposome's surface on the GI transit of insulin

Kazunori Iwanaga, Satoshi Ono, Kohji Narioka, Masawo Kakemi, Kazuhiro Morimoto, Shinji Yamashita, Yukihiro Namba, Naoto Oku

Journal:

Journal of Pharmaceutical Sciences

Year:

1999

Language:

english

File:

PDF, 65 KB

english, 1999

9

Gelatin Microspheres as a Pulmonary Delivery System: Evaluation of Salmon Calcitonin Absorption

KAZUHIRO MORIMOTO, HIDEYUKI KATSUMATA, TOSHIYUKI YABUTA, KAZUNORI IWANAGA, MASAWO KAKEMI, YASUHIKO TABATA, YOSHITO IKADA

Journal:

Journal of Pharmacy and Pharmacology

Year:

2000

Language:

english

File:

PDF, 99 KB

english, 2000

10

Pharmacokinetic-pharmacodynamic modelling of human insulin: validity of pharmacological availability as a substitute for extent of bioavailability

Makoto Miyazaki, Haruko Mukai, Kazunori Iwanaga, Kazuhiro Morimoto, Masawo Kakemi

Journal:

Journal of Pharmacy and Pharmacology

Year:

2001

Language:

english

File:

PDF, 263 KB

english, 2001

11

Kinetics of d-tubocurarine disposition and pharmacologic response in rats

Akira Morino, Kazunori Kitamura, Kazunori Katayama, Masawo Kakemi, Tamotsu Koizumi

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1983

Language:

english

File:

PDF, 738 KB

english, 1983

12

Effects of proteolytic enzyme inhibitors on nasal absorption of salmon calcitonin in rats

Kazuhiro Morimoto, Makoto Miyazaki, Masawo Kakemi

Journal:

International Journal of Pharmaceutics

Year:

1995

Language:

english

File:

PDF, 563 KB

english, 1995

13

Controlled release of plasmid DNA from hydrogels prepared from gelatin cationized by different amine compounds

Toshihiro Kushibiki, Ryuji Tomoshige, Kazunori Iwanaga, Masawo Kakemi, Yasuhiko Tabata

Journal:

Journal of Controlled Release

Year:

2006

Language:

english

File:

PDF, 222 KB

english, 2006

14

Controlled release of plasmid DNA from cationized gelatin hydrogels based on hydrogel degradation

Yasunori Fukunaka, Kazunori Iwanaga, Kazuhiro Morimoto, Masawo Kakemi, Yasuhiko Tabata

Journal:

Journal of Controlled Release

Year:

2002

Language:

english

File:

PDF, 942 KB

english, 2002

15

In vivo release and gene expression of plasmid DNA by hydrogels of gelatin with different cationization extents

Toshihiro Kushibiki, Ryuji Tomoshige, Yasunori Fukunaka, Masawo Kakemi, Yasuhiko Tabata

Journal:

Journal of Controlled Release

Year:

2003

Language:

english

File:

PDF, 293 KB

english, 2003

16

Application of polyethyleneglycol (PEG)-modified liposomes for oral vaccine: effect of lipid dose on systemic and mucosal immunity

Seiichiro Minato, Kazunori Iwanaga, Masawo Kakemi, Shinji Yamashita, Naoto Oku

Journal:

Journal of Controlled Release

Year:

2003

Language:

english

File:

PDF, 158 KB

english, 2003

17

Evaluation of gelatin microspheres for nasal and intramuscular administrations of salmon calcitonin

Kazuhiro Morimoto, Hideyuki Katsumata, Toshiyuki Yabuta, Kazunori Iwanaga, Masawo Kakemi, Yasuhiko Tabata, Yoshito Ikada

Journal:

European Journal of Pharmaceutical Sciences

Year:

2001

Language:

english

File:

PDF, 127 KB

english, 2001

18

Influence of absorption enhancers (bile salts) and the preservative (benzalkonium chloride) on mucociliary function and permeation barrier function in rabbit tracheas

Kazuhiro Morimoto, Yuriko Uehara, Kazunori Iwanaga, Masawo Kakemi, Yoshihiro Ohashi, Ayaki Tanaka, Yoshiaki Nakai

Journal:

European Journal of Pharmaceutical Sciences

Year:

1998

Language:

english

File:

PDF, 284 KB

english, 1998

19

Enhancing Effects of Unsaturated Fatty Acids with Various Structures on the Permeation of Indomethacin through Rat Skin

KAZUHIRO MORIMOTO, HIDEKI TOJIMA, TATSUO HARUTA, MASAO SUZUKI, MASAWO KAKEMI

Journal:

Journal of Pharmacy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 415 KB

english, 1996

20

In vitro transfection of plasmid DNA by cationized gelatin prepared from different amine compounds

Kushibiki, Toshihiro, Tomoshige, Ryuji, Iwanaga, Kazunori, Kakemi, Masawo, Tabata, Yasuhiko

Journal:

Journal of Biomaterials Science Polymer Edition

Year:

2006

Language:

english

File:

PDF, 1.49 MB

english, 2006

21

Kinetics of combined drug action

Tamotsu Koizumi, Masawo Kakemi, Kazunori Katayama

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1993

Language:

english

File:

PDF, 596 KB

english, 1993

22

Officers, Committees, and Representatives of the American Dairy Science Association, July 1969-June 1970

Ueda, Hiroshi, Kawai, Akira, Hayashi, Takashi, Ida, Yasuo, Kakemi, Masawo, Tozuka, Yuichi

Journal:

Journal of Dairy Science

Year:

1969

Language:

english

File:

PDF, 705 KB

english, 1969

23

Medical News.

Ueda, Hiroshi, Kawai, Akira, Hayashi, Takashi, Ida, Yasuo, Kakemi, Masawo, Tozuka, Yuichi

Journal:

Year:

1875

Language:

english

File:

PDF, 209 KB

english, 1875

24

Process monitoring of ultrasound compaction as a small-scale heating process

Ueda, Hiroshi, Kawai, Akira, Hayashi, Takashi, Ida, Yasuo, Kakemi, Masawo, Tozuka, Yuichi

Journal:

European Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 822 KB

english, 2013

25

THE LANCET.

Ueda, Hiroshi, Kawai, Akira, Hayashi, Takashi, Ida, Yasuo, Kakemi, Masawo, Tozuka, Yuichi

Journal:

Year:

1898

Language:

english

File:

PDF, 486 KB

english, 1898

26

Quantitative analysis of the effect of triglyceride alkyl-chain length on the partitioning of highly lipophilic compounds to the mesenteric lymph in intestinal cells

Iwanaga, Kazunori, Kawabata, Yutaka, Miyazaki, Makoto, Kakemi, Masawo

Journal:

Archives of Pharmacal Research

Year:

2014

Language:

english

File:

PDF, 378 KB

english, 2014

27

Time-dependent changes in hepatic and intestinal induction of cytochrome P450 3A after administration of dexamethasone to rats

Iwanaga, Kazunori, Honjo, Tatsuya, Miyazaki, Makoto, Kakemi, Masawo

Journal:

Year:

2013

Language:

english

File:

PDF, 462 KB

english, 2013

28

Effects of Low-Viscosity Sodium Hyaluronate Preparation on the Pulmonary Absorption of rh-Insulin in Rats

Morimoto, Kazuhiro, Metsugi, Kunihiko, Katsumata, Hideyuki, Iwanaga, Kazunori, Kakemi, Masawo

Journal:

Drug Development and Industrial Pharmacy

Year:

2001

Language:

english

File:

PDF, 159 KB

english, 2001

29

Enhancing mechanism of intestinal absorption of highly lipophilic compounds using microemulsion – Quantitative analysis of the partitioning to the mesenteric lymph in intestinal cells

Iwanaga, Kazunori, Higashiyama, Yoichi, Miyazaki, Makoto, Kakemi, Masawo

Journal:

Asian Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 875 KB

english, 2015

30

Pharmacokinetics and toxicity of repeated oral etoposide is altered by morphine coadministration in rats

Miyazaki, Makoto, Kawase, Tomoko, Nishimura, Chisako, Kitamura, Tomoko, Iwanaga, Kazunori, Kakemi, Masawo

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

2015

Language:

english

File:

PDF, 637 KB

english, 2015

31

Two-Layer Membrane Model for Iontophoretic Drug Transport through Excised Rat Skin.

INADA, Hirohiko, MIZUGUCHI, Kazue, KATAYAMA, Kazunori, KAKEMI, Masawo, KOIZUMI, Tamotsu

Journal:

Biological & Pharmaceutical Bulletin

Year:

1993

File:

PDF, 732 KB

1993

32

Tracheal Barrier and the Permeability of Hydrophilic Drugs and Dipeptides.

MORIMOTO, Kazuhiro, UEHARA, Yuriko, IWANAGA, Kazunori, KAKEMI, Masawo

Journal:

Biological & Pharmaceutical Bulletin

Year:

1999

File:

PDF, 724 KB

1999

33

Bioavailability Assessment of Disopyramide Using Pharmacokinetic-Pharmacodynamic(PK-PD) Modeling in the Rat.

MIYAZAKI, Makoto, MAEKAWA, Chieko, IWANAGA, Kazunori, MORIMOTO, Kazuhiro, KAKEMI, Masawo

Journal:

Biological & Pharmaceutical Bulletin

Year:

2000

File:

PDF, 1.09 MB

2000

34

Inhibitory Effects of Furanocoumarin Derivatives in Kampo Extract Medicines on P-Glycoprotein at the Blood–Brain Barrier

Iwanaga, Kazunori, Yoneda, Shinji, Hamahata, Yukimi, Miyazaki, Makoto, Shibano, Makio, Taniguchi, Masahiko, Baba, Kimiye, Kakemi, Masawo

Journal:

Biological & Pharmaceutical Bulletin

Year:

2011

Language:

english

File:

PDF, 574 KB

english, 2011

35

Pharmacokinetic Assessment of Absorptive Interaction of Oral Etoposide and Morphine in Rats

Miyazaki, Makoto, Nishimura, Chisako, Minamida, Minori, Iwanaga, Kazunori, Kakemi, Masawo

Journal:

Biological & Pharmaceutical Bulletin

Year:

2014

Language:

english

File:

PDF, 1.05 MB

english, 2014

36

Kinetic studies of the pharmacologic response to captopril in rats. II. Hypotensive effect and plasma angiotensin converting enzyme activity.

ENDOH, Makiko, SUZUKI, Masahiro, KATAYAMA, Kazunori, KAKEMI, Masawo, KOIZUMI, Tamotsu

Journal:

Journal of Pharmacobio-Dynamics

Year:

1989

File:

PDF, 734 KB

1989

37

Kinetic studies on drug disposition in rabbits. I. Renal excretion of iodopyracet and sulfamethizole.

KATAYAMA, Kazunori, OHTANI, Hiroyuki, KAWABE, Toshihiko, MIZUNO, Hiromoto, ENDOH, Makiko, KAKEMI, Masawo, KOIZUMI, Tamotsu

Journal:

Journal of Pharmacobio-Dynamics

Year:

1990

File:

PDF, 1.08 MB

1990

38

Kinetic studies of the pharmacologic response to captopril in rats. I. Role of the renin-angiotensin system.

ENDOH, Makiko, SUZUKI, Masahiro, KATAYAMA, Kazunori, KAKEMI, Masawo, KOIZUMI, Tamotsu

Journal:

Journal of Pharmacobio-Dynamics

Year:

1989

File:

PDF, 899 KB

1989

39

The pharmacodynamic and pharmacokinetic interaction of pentobarbital and chlorpromazine in rats.

HATANAKA, Tomomi, NEGISHI, Sachiko, KATAYAMA, Kazunori, KAKEMI, Masawo, KOIZUMI, Tamotsu

Journal:

Journal of Pharmacobio-Dynamics

Year:

1988

File:

PDF, 670 KB

1988

40

A kinetic study of chlorpromazine on the hyperglycemic response in rats. I. Effect of chlorpromazine on plasma catecholamines.

SATO, Shinji, MIZUNO, Sumiko, HATANAKA, Tomomi, OHSHIMA, Kouichi, ENDOH, Makiko, KATAYAMA, Kazunori, KAKEMI, Masawo, KOIZUMI, Tamotsu

Journal:

Journal of Pharmacobio-Dynamics

Year:

1988

File:

PDF, 668 KB

1988

41

Pharmacokinetic and pharmacodynamic studies of piretanide in rabbits. I. Effect of different hydrated conditions.

LU, WEI, ENDOH, MAKIKO, KATAYAMA, KAZUNORI, KAKEMI, MASAWO, KOIZUMI, TAMOTSU

Journal:

Journal of Pharmacobio-Dynamics

Year:

1987

File:

PDF, 825 KB

1987

42

Pharmacokinetic and pharmacodynamic studies of piretanide in rabbits. IV. Effects of piretanide on the proximal tubules and the loop of henle under a hydrated condition.

LU, Wei, KAKEMI, Masawo, KOIZUMI, Tamotsu

Journal:

Journal of Pharmacobio-Dynamics

Year:

1988

File:

PDF, 702 KB

1988

43

Effect of iodopyracet on renal excretion of sulfamethizole in rabbits.

KATAYAMA, Kazunori, TSUBOTA, Emi, ENDOH, Makiko, KAKEMI, Masawo, KOIZUMI, Tamotsu

Journal:

Journal of Pharmacobio-Dynamics

Year:

1990

File:

PDF, 706 KB

1990

44

A kinetic study of chlorpromazine on the hyperglycemic response in rats. II. Effect of chlorpromazine on plasma glucose.

SATO, Shinji, KATAYAMA, Kazunori, KAKEMI, Masawo, KOIZUMI, Tamotsu

Journal:

Journal of Pharmacobio-Dynamics

Year:

1988

File:

PDF, 1.05 MB

1988

45

Pharmacokinetic and pharmacodynamic studies of piretanide in rabbits. II: Effects on the proximal tubules and the loop of Henle.

LU, Wei, ENDOH, Makiko, KATAYAMA, Kazunori, KAKEMI, Masawo, KOIZUMI, Tamotsu

Journal:

Journal of Pharmacobio-Dynamics

Year:

1988

File:

PDF, 943 KB

1988

46

A pharmcokinetic model for enterohepatic circulation of an analgesic l-1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hex-ahydro-1,6-methano-1H-4-benzazonine hydrobromide (l-ST-2121) in rats.

KOIZUMI, TAMOTSU, KAKEMI, MASAWO, KATAYAMA, KAZUNORI, OGAWA, MICHITAKA

Journal:

Journal of Pharmacobio-Dynamics

Year:

1981

File:

PDF, 645 KB

1981

47

A note on saturable and inhibitory kinetics of p-aminohippurate renal transport in rabbits.

KOSHI, KATSUTOSHI, SHIRAI, YOKO, KATAYAMA, KAZUNORI, KAKEMI, MASAWO, UEDA, MICHIHIRO, KOIZUMI, TAMOTSU

Journal:

Journal of Pharmacobio-Dynamics

Year:

1983

File:

PDF, 732 KB

1983

48

Pharmacologic effects of metformin in relation to its disposition in alloxan diabetic rats.

KAKEMI, MASAWO, SASAKI, HIDEKI, SAEKI, KAZUE, ENDOH, MAKIKO, KATAYAMA, KAZUNORI, KOIZUMI, TAMOTSU

Journal:

Journal of Pharmacobio-Dynamics

Year:

1983

File:

PDF, 1.19 MB

1983

49

A kinetic study on chlorpromazine disposition and hypothermic response in rats.

SATO, SHINJI, NAKAGAWA, IKUKO, KATAYAMA, KAZUNORI, KAKEMI, MASAWO, KOIZUMI, TAMOTSU

Journal:

Journal of Pharmacobio-Dynamics

Year:

1986

File:

PDF, 885 KB

1986

50

Pharmacokinetic studies on pharmacologic response of captopril in rats.

ENDOH, MAKIKO, SUZUKI, MASAHIRO, KURODA, TOYOSHI, KATAYAMA, KAZUNORI, KAKEMI, MASAWO, KOIZUMI, TAMOTSU

Journal:

Journal of Pharmacobio-Dynamics

Year:

1985

File:

PDF, 669 KB

1985